lungs Aquilo

Rho-Kinase 1/2 Inhibition Prevents Transforming Growth Factor-β-Induced Effects on Pulmonary Remodeling and Repair

Wu X, Verschut V, Woest ME, Ng-Blichfeldt JP, Matias A, Villetti…
lungs Aquilo

Differential effects of pirfenidone and nintedanib on mouse alveolar epithelial organoids

Manon Woest, Vicky Verschut, Reinoud Gosens, Loes Kistemaker ERS…
lungs Aquilo

Pharmacological Screening Identifies SHK242 and SHK277 as Novel Arginase Inhibitors With Efficacy Against Allergen-Induced Airway Narrowing In Vitro and In Vivo

van den Berg MPM, Kurhade SH, Maarsingh H, Erceg S, Hulsbeek…
lungs Aquilo

Cholinergic Neuroplasticity in Asthma Driven by TrkB Signaling

Dragunas G, Woest ME, Nijboer S, Bos ST, van Asselt J, de Groot…
lungs Aquilo

Mesenchymal WNT-5A/5B Signaling Represses Lung Alveolar Epithelial Progenitors

Wu X, van Dijk EM, Ng-Blichfeldt JP, Bos IST, Ciminieri C, Königshoff…
lungs Aquilo

Second M3 Muscarinic Receptor Binding Site Contributes to Bronchoprotection by Tiotropium

Kistemaker LEM, Elzinga CRS, Tautermann CS, Pieper MP, Seeliger…